Early PKD Observational Cohort Study

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age4-35
SponsorUniversity of Kansas Medical Center

About this trial

This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also called a biorepository. The long-term goal is to develop new knowledge on biological markers or biomarkers that indicate changes in the disease progression. An understanding of biomarkers for early renal cyst growth will benefit PKD patients as new therapies are being developed and tested.

Eligibility criteria

Qualifiers

Family history of PKD

All races and ethnic groups

Glomerular filtration rate (GFR) >80 ml/min per 1.73 m2

Male or female with no family history of kidney disease

Disqualifiers

Non-insulin or insulin-dependent diabetes mellitus

Systemic illness (i.e.systemic lupus erythematosus, vasculitis)

Unable to provide written informed consent

Unavailable for magnetic resonance imaging (MRI) and blood/urine collection

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

250 Participants
are grouped into 3 trial groups

Sponsors and collaborators

University of Kansas Medical Center

Lead sponsor

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborator