About this trial
This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also called a biorepository. The long-term goal is to develop new knowledge on biological markers or biomarkers that indicate changes in the disease progression. An understanding of biomarkers for early renal cyst growth will benefit PKD patients as new therapies are being developed and tested.
Eligibility criteria
Qualifiers
Family history of PKD
All races and ethnic groups
Glomerular filtration rate (GFR) >80 ml/min per 1.73 m2
Male or female with no family history of kidney disease
Disqualifiers
Non-insulin or insulin-dependent diabetes mellitus
Systemic illness (i.e.systemic lupus erythematosus, vasculitis)
Unable to provide written informed consent
Unavailable for magnetic resonance imaging (MRI) and blood/urine collection
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
University of Kansas Medical Center
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator