Eating Disorders Genetics Initiative 2

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age12-99
SponsorUniversity of North Carolina, Chapel Hill

About this trial

The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes. The investigators are enrolling 20,000 new participants with anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), avoidant/restrictive food intake disorder (ARFID), and controls in the US, Mexico, Australia, New Zealand, Sweden, and Denmark. A primary study goal is to enroll at least 30% of participants from underrepresented groups. Participants are asked to complete a series of questionnaires and submit a saliva sample for genotyping. The goal is to better understand eating disorders and how they relate to each other so that better treatments can be developed.

Eligibility criteria

Qualifiers

A lifetime history of anorexia nervosa, bulimia nervosa, binge-eating disorder, avoidant restrictive food intake disorders or no history of any disordered eating behavior, based on DSM-5 criteria algorithms

Age 12-99 years, depending on country. (US enrollment age is 18-99)

Disqualifiers

History of subthreshold disordered eating behaviors.

Trial design

Treatments tested in this trial

  • Eating disorder diagnosis group

Treatment groups

20,000 Participants
are divided into 5 treatment groups

Sponsors and collaborators

University of North Carolina, Chapel Hill

Lead sponsor

Queensland Institute of Medical Research

Collaborator

Karolinska Institutet

Collaborator

National Institute of Mental Health (NIMH)

Collaborator

University of Otago

Collaborator

University of Aarhus

Collaborator

Yale University

Collaborator

Comenzar de Nuevo, AC

Collaborator

University of Sydney

Collaborator