About this trial
The goal of this interventional study is to assess the training effects in a training schedule in which eccentric overload training and eccentric cycle training are used.
Researchers will compare a training program of eccentric overload training and eccentric cycling training with a traditional training program of strength and cardio training in people with heart failure with reduced ejection fraction.
This study will be delivered in a cardiac rehabilitation setting.
Eligibility criteria
Qualifiers
HFrEF patients with ejection fraction <40%
Exercise intolerance (<85% of predicted VO2 peak)
clinically stable for > 6 weeks, optimal medical treatment for > 6 weeks
Disqualifiers
Contra indications for cardiac exercise rehabilitation as per consensus guidelines and recommendations
Musculoskeletal disorders that hamper (progression in) strength training
Non-stabilized acute coronary syndrome
Current acute heart failure (decompensation)
Trial design
Treatments tested in this trial
- eccentric bike training
- eccentric overload training
- aerobic treadmill training
- aerobic bike training
- traditional dynamic strength training