About this trial
1. Sufentanil as an strong analgesic is used widespreadly during laparoscopic cholecystectomy. 2. Lower dosages of sufentanil facilitated with dexmedetomidine can offer enough analgesia effect. 3. The investigator are planning use the most classical method for determining the ED50 or half effective concentration of sufentanil facilitated with dexmedetomidine using sequential method, which is also called" up and down method" and" ladder method".
Eligibility criteria
Qualifiers
ASA I ~ II level;
BMI22-30kg/m2;
Those who intend to undergo laparoscopic cholecystectomy;
Age 18~65 years.
Disqualifiers
Has been allergic to the drugs used in this study;
Patients with a history of chronic use of alcohol, smoke or other sedative drugs;
Patients took opioids and other analgesics before surgery;
Emergency operation;
Trial design
Treatments tested in this trial
- Not listed
Trial groups
6
Trial groupsSee each trial group below.