EEG and ANI Guided Anesthesia and Quality of Recovery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age19+
SponsorGangnam Severance Hospital

About this trial

This study aims to assess whether electroencephalogram (EEG) and nociception level-guided anesthesia can improve quality of recovery after laparoscopic gynecological surgery compared with standard care. Patients will be randomly assigned to either EEG and Analgesia Nociception Index (ANI)-guided anesthesia group (EEG-and-ANI-Guided group) or usual care group (control group). Primary outcome is 15-item Quality of Recovery (QoR-15) score at postoperative day (POD) 1. Secondary outcomes included remifentanil consumption during anesthesia, occurrence of awareness with recall, incidence of undesirable intraoperative movement, emergence time, postoperative pain scores, quality of recovery score at POD 2, and length of hospital stay.

Eligibility criteria

Qualifiers

Total laparoscopic hysterectomy with/without salpingo-oophorectomy

Laparoscopic myomectomy

Laparoscope-guided salpingo-oophorectomy

Laparoscope-guided ovarian cystectomy

Disqualifiers

Patients with nonregular sinus cardiac rhythm

Patients with implanted pacemakers

Patients on antimuscarinic agents, α2-adrenergic agonists, β1-adrenergic antagonists, antiarrhythmic agents

pregnant or breastfeeding women

Trial design

Treatments tested in this trial

  • EEG-and-ANI-guided anesthesia
  • standard anesthesia
  • Sevoflurane and remifentanil
  • EEG and ANI

Treatment groups

126 Participants
are divided into 2 treatment groups

Sponsors and collaborators