About this trial
This is a randomized, sham controlled study of the Electroencephalogram (EEG) based Transcranial Magnetic Stimulation (eTMS) treatment for Post-Traumatic Stress Disorder (PTSD). The recruitment goal is 110 participants who are United States Military veterans or first responders (e.g., firefighters, police, paramedics, etc.). The Study includes an EEG recording in order to determine the optimal treatment parameters for the eTMS system, followed by 15 in-office visits that take place over 21-28 total days. Two eTMS treatment sessions are administered during each office visit.
Eligibility criteria
Qualifiers
Willing and able to consent to participate in the study via signed Informed Consent
Age 22 - 65 years
Diagnosis of PTSD according to DSM-5 criteria via the Clinician-Administered PTSD Scale (CAPS).
Onset of symptoms meeting the DSM-5 criteria for PTSD symptoms persisting for a minimum of 6 months prior to the Screening Visit
Disqualifiers
Uncontrolled medical, psychological or neurological condition
Pregnant, or female unwilling to use effective birth control during the course of the trial
Metal objects in the head
Past exposure to metal fragments, permanent piercings, and/or other possible metal sources in the head and neck
Trial design
Treatments tested in this trial
- EEG-based personalized TMS
- Sham Comparator