EEG-based Personalized Transcranial Magnetic Stimulation (eTMS) to Treat Post-Traumatic Stress Disorder

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age22-65
SponsorWave Neuroscience

About this trial

This is a randomized, sham controlled study of the Electroencephalogram (EEG) based Transcranial Magnetic Stimulation (eTMS) treatment for Post-Traumatic Stress Disorder (PTSD). The recruitment goal is 110 participants who are United States Military veterans or first responders (e.g., firefighters, police, paramedics, etc.). The Study includes an EEG recording in order to determine the optimal treatment parameters for the eTMS system, followed by 15 in-office visits that take place over 21-28 total days. Two eTMS treatment sessions are administered during each office visit.

Eligibility criteria

Qualifiers

Willing and able to consent to participate in the study via signed Informed Consent

Age 22 - 65 years

Diagnosis of PTSD according to DSM-5 criteria via the Clinician-Administered PTSD Scale (CAPS).

Onset of symptoms meeting the DSM-5 criteria for PTSD symptoms persisting for a minimum of 6 months prior to the Screening Visit

Disqualifiers

Uncontrolled medical, psychological or neurological condition

Pregnant, or female unwilling to use effective birth control during the course of the trial

Metal objects in the head

Past exposure to metal fragments, permanent piercings, and/or other possible metal sources in the head and neck

Trial design

Treatments tested in this trial

  • EEG-based personalized TMS
  • Sham Comparator

Treatment groups

110 Participants
are divided into 2 treatment groups

Sponsors and collaborators