About this trial
This study assesses the effects of a probiotic or postbiotic on gut microbiome during antibiotic treatment.
Eligibility criteria
Qualifiers
Males and females aged ≥18 to ≤ 65 years; if female, either not of childbearing potential or using a medically approved method of birth control and willing to take a pregnancy test at screening.
Body mass index (BMI) 18.5-29.9 kg/m².
Healthy as determined by medical history and physical examination.
Agreed not to change current dietary habits during the course of the study.
Disqualifiers
Women who are pregnant, breastfeeding, or planning to become pregnant during the course of the study.
People on vegetarian or vegan diet; People on special diet (e.g. Ducan, Keto, etc.)
BMI ≥ 30 kg/m² or <18.5 kg/m².
History of intake of antibiotics, other probiotics, postbiotics, prebiotics, synbiotics, proton pump inhibitors, acid sequestrants (cholestyramine, Bile colestipol), within six months prior to the screening day.
Trial design
Treatments tested in this trial
- Probiotic
- Postbiotic
- Placebo
Treatment groups
Sponsors and collaborators
The Archer-Daniels-Midland Company
Lead sponsor
NEXT CRO
Collaborator