Effect of a Probiotic or Postbiotic on Gut Microbiome During Antibiotic Treatment

ConditionMicrobiome
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorThe Archer-Daniels-Midland Company

About this trial

This study assesses the effects of a probiotic or postbiotic on gut microbiome during antibiotic treatment.

Eligibility criteria

Qualifiers

Males and females aged ≥18 to ≤ 65 years; if female, either not of childbearing potential or using a medically approved method of birth control and willing to take a pregnancy test at screening.

Body mass index (BMI) 18.5-29.9 kg/m².

Healthy as determined by medical history and physical examination.

Agreed not to change current dietary habits during the course of the study.

Disqualifiers

Women who are pregnant, breastfeeding, or planning to become pregnant during the course of the study.

People on vegetarian or vegan diet; People on special diet (e.g. Ducan, Keto, etc.)

BMI ≥ 30 kg/m² or <18.5 kg/m².

History of intake of antibiotics, other probiotics, postbiotics, prebiotics, synbiotics, proton pump inhibitors, acid sequestrants (cholestyramine, Bile colestipol), within six months prior to the screening day.

Trial design

Treatments tested in this trial

  • Probiotic
  • Postbiotic
  • Placebo

Treatment groups

126 Participants
are divided into 3 treatment groups

Sponsors and collaborators