Effect of Acupuncture on Mild to Moderate Active Crohn's Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age16-70
SponsorShanghai Institute of Acupuncture, Moxibustion and Meridian
About this trial
To observe the clinical effect of acupuncture on Crohn's disease (CD) and its influence on brain function activity and the TRY-KYN metabolism level, and to screen the brain image markers of acupuncture on CD
Eligibility criteria
Qualifiers
aged 16-70;
patients with mild or moderate active disease (150 ≤ CDAI < 450);
patients who are not responsive, intolerant, dependent or refused to use at least mesalazine, glucocorticoid, immunomodulator (azathioprine, methotrexate), anti TNF alpha preparation;
patients were not taking medication or were only taking one or more of the following drugs: [prednisone ≤15mg/d, azathioprine (≤1mg/kg/d), methotrexate (≤15mg/w) or mesalazine (≤4g/d)] and prednisone was used for at least 1 month, while azathioprine, methotrexate or mesalazine was used for at least 3 months;
Disqualifiers
patients who are recently pregnant or in pregnancy or lactation;
patients with serious organic diseases;
patients diagnosed as psychosis;
patients who take antibiotics, probiotics, traditional Chinese medicine and other drugs at the same time, or who suffer from multiple diseases and need to take other drugs for a long time, and may affect the observation of the efficacy of this trial;
Trial design
Treatments tested in this trial
- acupuncture
Treatment groups
60 Participants
are divided into 1 treatment groupSponsors and collaborators
Shanghai Institute of Acupuncture, Moxibustion and Meridian
Lead sponsor
Fudan University
Collaborator
Shanghai University of Traditional Chinese Medicine
Collaborator
Shanghai Jiao Tong University School of Medicine
Collaborator
Indiana University
Collaborator
Source ClinicalTrials.gov