About this trial
This study aims to determine the effect of adenotonsillectomy (AT) surgery on the progression of spinal curvature in children with mild sleep-disordered breathing (SDB) and concurrent scoliosis, as well as its potential role in preventing the de novo development of scoliosis in children with SDB.
Eligibility criteria
Qualifiers
Age between 6 and 15 years.
Diagnosed with mild SDB, defined as: Obstructive Apnea-Hypopnea Index (OAHI) ≤5 events/hour on a laboratory-based PSG performed within the past 6 months, AND parental report of habitual obstructive breathing symptoms (e.g., snoring, mouth-breathing, witnessed apneas) occurring >3 nights per week on average.
Tonsillar hypertrophy grade ≥2 (on a scale of 0-4) and deemed an appropriate candidate for AT upon ENT evaluation (i.e., no absolute contraindications such as submucous cleft palate).
Has undergone radiographic screening for idiopathic scoliosis at the first clinic visit.
Disqualifiers
Unwillingness or inability to comply with study procedures.
Plans to relocate outside the study area within 24 months.
Previous tonsillectomy or adenoidectomy.
Recurrent tonsillitis meeting guideline criteria for immediate AT.
Trial design
Treatments tested in this trial
- Adenotonsillectomy (AT) - removal of adenoids and tonsils
- Watchful Waiting with Supportive Care
Treatment groups
Sponsors and collaborators
Second Affiliated Hospital of Wenzhou Medical University
Lead sponsor
The Children's Hospital of Zhejiang University School of Medicine
Collaborator
Ningbo No. 1 Hospital
Collaborator
Ningbo No.2 Hospital
Collaborator
The Third Affiliated Hospital of Wenzhou Medical University
Collaborator