Effect of Aerobic Exercise on Biomarkers in Depression
ConditionMajor Depression
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-40
SponsorKutahya Health Sciences University
About this trial
This study aims to investigate changes in the levels of biomarkers (IGF-1, FGF2, and EGF) involved in neuron development in patients diagnosed with major depression through the effects of breathing exercises and aerobic exercise, as well as to examine the levels of biomarkers (TNF-α, IL-6, and IL-1) and oxidative stress (TAS, TOS, MDA, and F2-isoprostane) that are thought to play a role in the pathophysiology of depression.
Eligibility criteria
Qualifiers
Individuals who volunteer to participate in the study,
Between the ages of 18 and 40,
Have been diagnosed with clinical depression by a psychiatrist according to DSM-5 criteria
Disqualifiers
Individuals with chronic conditions accompanying depression,
Those with walking difficulties
Those with respiratory system disorders
Trial design
Treatments tested in this trial
- Breathing exercise
- Aerobic Exercise
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
Kutahya Health Sciences University
Lead sponsor
Scientific Research Projects Coordination Unit
Collaborator
Source ClinicalTrials.gov