Effect of Aerobic Interval Training on Atrial Fibrillation Burden

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-74
SponsorNavy General Hospital, Beijing

About this trial

Atrial fibrillation is the most common arrhythmia, with an increasing incidence and prevalence, significantly increasing the risk of death, stroke, heart failure, cognitive impairment, and dementia, severely impacting the quality of life for patients and burdening society and healthcare systems. In recent years, exercise-based cardiac rehabilitation has gradually become a new approach for the treatment of patients with heart disease. The main research topics include: 1. Changes in atrial fibrillation burden in non-permanent atrial fibrillation patients after 12 weeks of HIIT(high-intensity interval training ) or MIIT (moderate-intensity interval training). 2. Changes in cardiorespiratory fitness, quality of life scores, mental health assessment scores, atrial strain, and left ventricular diastolic function in non-permanent atrial fibrillation patients after 12 weeks of aerobic interval training, along with follow-up on the occurrence of exercise-related adverse events and adverse cardiovascular events during the study period.

Eligibility criteria

Qualifiers

Age range: 18-74 years;

Patients with non-permanent atrial fibrillation;

Resting heart rate ≤110 beats/min;

No history of receiving a formal exercise prescription within the past six months;

Disqualifiers

History of myocardial infarction, endocarditis/myocarditis/pericarditis, stroke (ischemic/hemorrhagic), pulmonary embolism, lower extremity venous thrombosis, or cardiac surgery within the past 6 months;

Moderate to severe pulmonary arterial hypertension, moderate to severe valvular heart disease, hypertrophic cardiomyopathy, aortic stenosis/dilation/dissection/intramural hematoma, congenital heart disease;

Heart failure (NYHA class III-IV) or acute exacerbation of heart failure within the past 3 months;

Unstable angina or severe coronary artery disease without revascularization;

Trial design

Treatments tested in this trial

  • high-intensity interval training
  • moderate-intensity interval training

Treatment groups

156 Participants
are divided into 3 treatment groups

Sponsors and collaborators