Constitutional Thinness (CT) is a form of stable thinness without malnutrition but with resistance to weight gain, affecting approximately 1% of the general population. The clinical consequences are numerous and the pathophysiology remains poorly understood.
Currently, conventional management involves a high-calorie and frequent diet, combined with the avoidance of endurance physical activity, although there is no significant evidence of its effectiveness.
Our hypothesis is that an adapted physical activity program (APA) combined with compensatory nutrition (CN) could help these patients gain lean mass (muscle mass).
Gender: Female
BMI: ≤ 18.5 kg/m²
Weight Stability: Stable weight for at least 3 months
Age: 18 to 50 years old at the inclusion visit
Pregnancy, Parturition, or Lactation
Legal Restrictions: Individuals deprived of liberty, involuntarily hospitalized, or hospitalized for reasons other than research purposes, adults under legal protection (guardianship or curatorship) or unable to provide consent
Eating Disorders: Individuals with eating disorders (DSM IV and 5 criteria)
Excessive Alcohol Consumption: Consumption exceeding the equivalent of 10 glasses of wine per week
Centre Hospitalier Universitaire de Saint Etienne
Lead sponsor
Laboratoire Interuniversitaire de Biologie de la Motricité
Collaborator
Target Tape
Collaborator