Effect of Antioxydant-enriched Media on Blastocyst Euploidy Rates.
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-43
SponsorART Fertility Clinics LLC
About this trial
One of the most sensible factors in IVF culture conditions is the susceptibility of gametes and embryos to an induced increase in reactive oxidative species (ROS) caused by the artificial environment. This study aims to evaluate the impact of using antioxidant-supplemented media during culture to evaluate embryo ploidy rates in a prospective randomized trial using sibling oocytes.
Eligibility criteria
Qualifiers
Patients undergoing assisted reproductive technology cycles when ICSI is indicated.
Patients when Iin vitto fertilization (IVF) is also performed will be included as far as there are enough oocytes for ICSI randomization. However, IVF oocytes will not be used for the study.
Maternal age 18-43 years old.
PGT-A cycles with only trophectoderm biopsies on day 5/6/7.
Disqualifiers
PGT-M cycles
Fresh and frozen testicular sperm.
Trial design
Treatments tested in this trial
- antioxidants-enriched culture medium (Gx)
Treatment groups
500 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov