Effect of Apical Patency and Local Corticosteroid on Pain and Neuropeptides Release in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-60
SponsorSuez Canal University

About this trial

The goal of this randomized clinical trial is to learn the effect of using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis in molar teeth. The main question it aims to answer is:

• How effective are using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis? Participants will be asked to fill a visual analogue scale to record their pain, after receiving a root canal treatment while using local corticosteroids or not as well as maintaining apical patency or not.

Researchers will compare the use of corticosteroids and maintaining apical patency in reducing post-operative pain.

Eligibility criteria

Qualifiers

Symptomatic acute irreversible pulpitis in molar teeth.

Normal periapical condition including periapical radiography with minimal widening of periodontal ligament.

Normal probing depth.

No medical condition.

Disqualifiers

Facial or oral paresthesia.

Pregnancy & breastfeeding.

Unrestorable tooth.

Marginal periodontal disease.

Trial design

Treatments tested in this trial

  • Non-corticosteroid injection
  • Corticosteroid injection

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators