Effect of Bariatric Surgery Versus Medical Therapy on Metabolic Syndrome

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorThird Military Medical University

About this trial

Bariatric surgery (BS) is known to improve the components of metabolic syndrome (MS) in obese patients. However, few studies have evaluated the impact of bariatric surgery versus medical therapy (MT) in patients with MS, especially in patients with low body mass index (BMI). This study aimed to assess the effect of bariatric surgery on MS in patients with low BMI by comparing BS (BMI\<35 kg/m2 and BMI≥35 kg/m2) with MT (BMI\<35 kg/m2). A retrospective study including patients with MS undergoing bariatric surgery and medical therapy at a single institution. We follow up the 5 years effect of bariatric surgery versus medical therapy on the remission of MS, its individual components, atherosclerotic cardiovascular disease (ASCVD) risk, and medication used.

Eligibility criteria

Qualifiers

BMI<35 kg/m²

Underwent bariatric surgery or medical therapy

Patients met the diagnostic criteria for MS, defined criteria derived from the joint interim statement (JIS)

Disqualifiers

Patients who failed to follow up

Insulin dependent diabetes

congenital dementia

brain trauma

Trial design

Treatments tested in this trial

  • Hypoglycemic drugs
  • Bariatric surgery

Treatment groups

200 Participants
are divided into 2 treatment groups