Effect of Caffeine on Cold-stimulated Brown Adipose Tissue Activity
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-40
SponsorUniversity Hospital, Basel, Switzerland
About this trial
The purpose of the study is to asses brown adipose tissue activity after a cold mild stimulus, preceded by 200mg caffeine or placebo administration.
Eligibility criteria
Qualifiers
BMI 18.5 to 25 kg/m2
Able to give informed consent as documented by signature
Moderate caffeine consumption (1 to 3 cups of coffee per day)
Increase of EE in response to mild cold of ≥ 5% of REE
Disqualifiers
Known hypersensitivity or allergy to caffeine
Concomitant medication other than prescription free analgesics (paracetamol and NSAID) and oral contraceptives
Other clinically significant concomitant disease states (e.g., renal failure, hepatic dysfunction, cardiovascular disease, cardiac arrhythmia, hypertension, diabetes mellitus, hyper- or hypothyroidism)
History of depressive disorder or anxiety disorder
Trial design
Treatments tested in this trial
- Caffeine (200 mg)
- Placebo
Treatment groups
12 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov