This is a prospective, single-arm, pretest-posttest study evaluating the effects of a 21-day comprehensive spa treatment (Komplexní lázeňská léčebně rehabilitační péče, KLP) on female infertility at spa facility in Františkovy Lázně, Czech Republic.
The study enrolls 55 women aged 20-40 years diagnosed with infertility. The primary objective is to assess changes in hormonal profile before and after treatment.
Secondary objectives include evaluation of body composition, psychometric outcomes and long-term reproductive outcomes.
Female, age 20-40 years
Diagnosis of infertility (primary or secondary)
History of at least one unsuccessful embryo transfer
Contraindications to spa treatment
Acute gynecological inflammation
Severe comorbidities affecting study outcomes
Oncological disease
Institute of Spa and Balneology, public research institution
Lead sponsor
Františkovy lázně
Collaborator