Effect of CoQ10 on the Endocrine Function of Skeletal Muscle
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age21-29
SponsorMedical University of Gdansk
About this trial
Recent studies have also shown that repeated episodes of ischemia, followed by reperfusion (IPC), can contribute to the development of adaptive changes not only in the area of the heart muscle, but also in the structure of the skeletal muscles.
In the project, several research questions will be evaluated e.g. what is the relationship between oxidative stress parameters, uric acid concentration and nitric oxide degradation products in groups of people undergoing two-week training in ischemic training, or what is the relationship between the expression of genes associated with muscle cell growth (e.g. myostatin gene) and the effect of ischemia preconditioning training etc.
Eligibility criteria
Qualifiers
gender (males only),
not taking medication during the study,
good health (no concomitant injuries),
negative history of cardiovascular disorders, autonomic nervous system, mental disorders, cerebrospinal injuries and other diseases that may directly affect the results obtained.
Disqualifiers
None
Trial design
Treatments tested in this trial
- CoQ10 supplementation
- Ischemic preconditioning training
- IPC training combined with CoQ10 supplementation
- Sham IPC combined with placebo
Treatment groups
100 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov