Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery

ConditionChalazion
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1-6
SponsorJoint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong

About this trial

This randomized controlled trial aims to compare the effectiveness and safety of 6% versus 8% sevoflurane inhalation induction in pediatric patients undergoing minor ophthalmic surgery. The primary outcome is emergence agitation assessed using the Pediatric Anesthesia Emergence Delirium (PAED) scale. Secondary outcomes include hemodynamic parameters, induction time, recovery time, and adverse events.

Eligibility criteria

Qualifiers

Children aged 1 to 6 years (12-72 months)

Scheduled to undergo minor ophthalmic surgery (e.g., chalazion excision) under general anesthesia

American Society of Anesthesiologists (ASA) physical status I

Assessed as suitable for inhalation anesthesia by anesthesiologists

Disqualifiers

ASA physical status II or higher

Known hepatic or renal dysfunction

Congenital heart disease

History of malignant hyperthermia

Trial design

Treatments tested in this trial

  • Sevoflurane

Treatment groups

80 Participants
are divided into 2 treatment groups