The purpose of this study is to quantitatively investigate the radiographic changes of alveolar bone, and gingival tissue changes of the mandibular anterior teeth in experimental group A receiving SFOT using freeze-dried allograft with a collagen membrane, experimental group B receiving SFOT using particulate xenograft covered by a collagen membrane and control group receiving only orthodontics therapy.
American Society of Anesthesiologists (ASA) I/II
Periodontal diagnosis of clinical gingival health or gingivitis on intact/reduced periodontium per 2017 American Academy of Periodontology (AAP) classification
No history of periodontitis.
Class I malocclusion
Patients who are current smokers
Pregnancy
Uncontrolled diabetes or other metabolic systemic conditions
Presence of open bite or deep bite
The University of Texas Health Science Center, Houston
Lead sponsor
American Academy of Periodontology Foundation
Collaborator