This study will be the first in the literature to evaluate the relationship between aerobic and resistance exercises, plasma amino acid levels, metabolic control of patients, and the metabolic response to exercise with different types of meals in patients with Phenylketonuria (PKU). In patients with phenylketonuria, the aim is to determine which pre-exercise dietary recommendations are more physiologically appropriate and ideal for achieving good metabolic control.
In the literature, there are very few studies examining the effects of exercise on plasma amino acid levels and metabolic parameters in PKU patients.
Be over 18 years old,
Having a classic FKU diagnosis,
Not being actively engaged in sports,
Not having any other existing diseases,
Presence of a chronic disease accompanying FKU disease (endocrine, etc.)
The individual with FKU has mental retardation or is deemed unfit for work based on psychomotor assessment,
Recent weight loss, history of hospitalisation, a past infection, or a diagnosed illness
Use of drugs or alcohol that alter protein and energy metabolism (e.g., corticosteroids, etc.)
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Treatment groupsSee each treatment group below.