Effect of Different Root Canal Sealers on Oxidative Stress Markers
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
Sponsorbengi gülgü
About this trial
The goal of this clinical trial is to primary purpose investigate and compare oxidative stress markers in patients with chronic apical periodontitis treated with different root canal paste in a single session. The main questions it aims to answer are:
Is there a change in oxidative stress markers measured from saliva after root canal treatment? Is there a difference between the change of oxidative stress markers in patients using different root canal sealers after root canal treatment?
Researchers will compare bioceramic-based and epoxy resin-based root canal sealers to see if there are significant differences in oxidative stress markers measured from patients' saliva after root canal treatment.
* Participants will be informed about all procedures before starting the clinical process. * Participants are expected to allow saliva sampling two times: first sample will be collected on root canal treatment session and second sample will be collected on the 30th day after root canal treatment. * Participants will be informed in writing about the treatment procedure before starting the clinical process. * Participants are expected to sign the informed consent form on a voluntary basis.
Eligibility criteria
Qualifiers
Systemically healthy, ASA1 patients,
Phase 1 periodontal treatment was performed,
Diagnosed with chronic apical periodontitis in a single tooth with 2 or more roots in the mouth,
The lesion measured <2 cm on radiographic evaluation,
Disqualifiers
Patients who have used antibiotics in the last three months and analgesics in the last two weeks
Patients who smoke and/or abuse alcohol
Patients younger than 18 years or older than 45 years,
Patients with controlled or uncontrolled systemic disease and life-threatening conditions (ASA 2,3,4,5,6)
Trial design
Treatments tested in this trial
- Root Canal Treatment and Sample Collection
- PAI Score Comparasion
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
bengi gülgü
Lead sponsor
Ordu University
Sponsor institution
Source ClinicalTrials.gov