About this trial
This randomised crossover study's primary aim is to investigate the effect of short-term fasting (eTRE) on subjective appetite and appetite-regulatory hormones (i.e., leptin, adiponectin, total glucagon-like peptide-1 (GLP-1), gastric inhibitory polypeptide (GIP), total peptide YY (PYY), acylated ghrelin and Insulin). In addition, to examine if the one-day early time-restricted eating influences energy expenditure and ad libitum energy intake in the periods following the standard meal test. The researchers will compare normal eating with early Time-Restricted Eating (eTRE) in healthy men.
Eligibility criteria
Qualifiers
Males aged 18 years or older.
BMI between 18.5 and 24.9 kg/m²
Have stable body mass for at least three months (within ±2 kg).
Disqualifiers
Females
People who are younger than 18 or older than 65 years old.
Following a special diet (e.g. weight loss, vegetarian or vegan, etc.).
Have food allergies related to the study.
Trial design
Treatments tested in this trial
- Normal diet
- early Time-Restricted Eating (eTRE)
- instantaneous visual analogue scale (iVAS)
Treatment groups
Sponsors and collaborators
University of Glasgow
Lead sponsor
University of Jazan
Collaborator