Effect of Early Time-Restricted Eating on Appetite, Appetite-Regulatory Hormones and Energy Intake

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18-65
SponsorUniversity of Glasgow

About this trial

This randomised crossover study's primary aim is to investigate the effect of short-term fasting (eTRE) on subjective appetite and appetite-regulatory hormones (i.e., leptin, adiponectin, total glucagon-like peptide-1 (GLP-1), gastric inhibitory polypeptide (GIP), total peptide YY (PYY), acylated ghrelin and Insulin). In addition, to examine if the one-day early time-restricted eating influences energy expenditure and ad libitum energy intake in the periods following the standard meal test. The researchers will compare normal eating with early Time-Restricted Eating (eTRE) in healthy men.

Eligibility criteria

Qualifiers

Males aged 18 years or older.

BMI between 18.5 and 24.9 kg/m²

Have stable body mass for at least three months (within ±2 kg).

Disqualifiers

Females

People who are younger than 18 or older than 65 years old.

Following a special diet (e.g. weight loss, vegetarian or vegan, etc.).

Have food allergies related to the study.

Trial design

Treatments tested in this trial

  • Normal diet
  • early Time-Restricted Eating (eTRE)
  • instantaneous visual analogue scale (iVAS)

Treatment groups

12 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Glasgow

Lead sponsor

University of Jazan

Collaborator