Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars

ConditionCaries,Dental
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-12
SponsorAlexandria University

About this trial

Background: Subjecting human dental enamel to sub-ablative laser has been suggested as a novel way of caries prevention. However, further studies are needed to establish its use as a routine clinical procedure for caries prevention.

The aim of this study: This study aims to evaluate the effect of Er,Cr:YSGG subablative laser irradiation on caries resistance of occlusal fissures of permanent molars.

Materials and methods: In-vivo study, a split mouth randomized controlled trial with sixty patients having two fully erupted bilateral first permanent molars (ICDAS-II score 0,1 or 2). The pits and fissures will be subjected to sub-ablative power of Er,Cr:YSGG Laser (Group 1, n=90) and will be compared with fluoride varnish application on the first permanent molars in the same arch(Group 2,n=90). DIAGNOdentTM readings and changes in ICDAS-II score will be assessed at base line and at 3,6,9 and 12 months follow-up.

Eligibility criteria

Qualifiers

Participants of age 6-12 years old

Patients ranking definitely positive or positive on Frankl behavior rating scale

Having at least two bilateral fully erupted first permanent molars with untreated non-cavitated occlusal surfaces with deep grooves, the included teeth will have International Detection and Assessment System (ICDAS-II)/ severity scores 0, 1 or 2

Initial DIAGNOdent Score not exceeding value of 25 indicating only enamel involvement

Disqualifiers

Patients with any known medical history of systemic diseases

Patients having first permanent molar with hypoplastic or hypocalcified enamel

Patients using medications that may affect the oral flora or salivary flow

Patients treated with in-office fluoride treatment within the last 3 months prior to being enrolled in the study.

Trial design

Treatments tested in this trial

  • sub-ablative Er,Cr:YSGG laser
  • Fluoride varnish application

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators