Effect of Exercise Gene Expression and Histone Modifications in Patients With Hemiplegia

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age25-70
SponsorAfyonkarahisar Health Sciences University

About this trial

The aim of this study is to demonstrate the effect of routine exercise program on neuroplasticity through histone acetylation and gene expression changes in acute stroke survivors from an epigenetic perspective and to investigate the correlation of epigenetic effects with its effects on motor function and quality of life.

Eligibility criteria

Qualifiers

Participants who applied to Afyonkarahisar Health Sciences University Physical Therapy and Rehabilitation Clinic for rehabilitation purposes and had a stroke for the first time

Participants with ischemia as the etiology of stroke

Participants between the ages of 25-70

Drugs that have been used for at least 1 month and up to 6 months after a cerebrovascular accident

Disqualifiers

Participants whose stroke etiology is other than ischemia

Participants with clinically significant neurological disease other than stroke

Participants with systemic and musculoskeletal diseases that will not tolerate neurological rehabilitation and prevent them from participating

Trial design

Treatments tested in this trial

  • Physiotherapy and Rehabilitation Practices

Treatment groups

48 Participants
are divided into 1 treatment group