About this trial
A randomized, controlled, cross-over post-prandial trial in healthy human volunteers will be conducted at the IH Asper Institute to determine the effect whole ground flaxseed, roasted then ground whole flaxseed, whole intact flaxseed and flaxseed hulls mixed into yogurt on blood cyanide levels.
Eligibility criteria
Qualifiers
Generally healthy adult, 18 years or older;
Willing to provide informed consent;
Willing/able to comply with the requirements of the study.
Disqualifiers
Pregnant or lactating;
Medical history of disease that is currently under treatment;
Active treatment for any type of cancer within 1 year prior to study start;
Presence of a gastrointestinal disorder, daily use of any stomach acid-lowering medications or laxatives (including fibre supplements) within the past month or antibiotic use within the past 6 weeks;
Trial design
Treatments tested in this trial
- 0 g Flax
- 40 g whole ground flaxseed
- 40 g roasted then ground whole flaxseed
- 40 g of whole intact flaxseeds
- 28 g flax hulls
Treatment groups
Sponsors and collaborators
St. Boniface Hospital
Lead sponsor
Agriculture and Agri-Food Canada
Collaborator