Effect of Fluoride Varnish Formulation on the Management of Dentin Hypersensitivity

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-40
SponsorUniversity of Concepcion, Chile

About this trial

This randomized controlled clinical trial aims to determine whether different fluoride varnish formulations reduce dentin hypersensitivity (DH) in young adults diagnosed with DH. The primary purpose of this study is to evaluate the clinical effectiveness of two commercially available fluoride varnishes.

The main questions this study aims to answer are:

* Does Clinpro Clear® (aqueous base, 9,500 ppm NaF) lead to a greater reduction in dentin hypersensitivity compared with Duraphat® (rosin/resin base, 22,600 ppm NaF)? * Do these varnish formulations improve oral health-related quality of life and patient satisfaction?

Researchers will compare a single application of Duraphat® with a single application of Clinpro Clear® to assess differences in hypersensitivity reduction, quality-of-life outcomes, and patient satisfaction.

Participants will:

* Receive one application of either Duraphat® or Clinpro Clear® under standardized clinical conditions. * Complete baseline and post-treatment evaluations, including: * Dentin hypersensitivity intensity using a visual analogue scale (VAS) * Air-blast response using the Schiff scale * Oral health-related quality of life using the OHIP-14 * Patient satisfaction using the CSAT survey

Eligibility criteria

Qualifiers

Age between 18 and 40 years

Absence of systemic diseases with oral manifestations or requiring medications with antisialagogue effects

Fully dentate (excluding third molars or teeth extracted for orthodontic reasons)

Absence of periodontal disease, or periodontal condition in a stable state

Disqualifiers

Patients requiring long-term use of NSAIDs or other analgesic/anti-inflammatory medications

Patients with allergy to milk proteins

Patients with allergy to organic resins or pine-derived substances

Pregnant or breastfeeding individuals

Trial design

Treatments tested in this trial

  • Aqueous fluoride varnish, 9,500 ppm NaF
  • Resin/rosin-based varnish, 22,600 ppm NaF

Treatment groups

92 Participants
are divided into 2 treatment groups

Sponsors and collaborators