Effect of FODMAP Diet on Pain, Quality of Life, and Sexual Function in Women With Pelvic Endometriosis and Gastrointestinal Symptoms

ConditionEndometriosis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorFondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

About this trial

The main objective of the study is to assess whether a dietary regimen based on the principles of the FODMAP diet, compared with the current treatment programme which does not include specific dietary recommendations, can improve pain symptoms in patients with symptomatic endometriosis and intestinal symptoms (i.e. bloating, nausea, constipation, diarrhoea and vomiting) attributable to irritable bowel syndrome, compared with a control group

Eligibility criteria

Qualifiers

Age between 18 and 45 years

BMI between 18.5 and 24.9,

Surgical, clinical or instrumental diagnosis of endometriosis

Presence of bowel symptoms (i.e., bloating, nausea, constipation, diarrhea, and vomiting) referable to irritable bowel syndrome, on estro-progestin or progestin treatment or in the absence of hormonal treatment

Disqualifiers

Associated conditions that may cause pelvic pain independent of the presence of endometriosis (e.g., pelvic varices and salpingitis outcomes)

chronic inflammatory bowel disease (Crohn's disease or ulcerative rectocolitis).

patients with obstructive uropathy, subocclusive intestinal stenosis

complex adnexal masses or typical endometriomas greater than 5 cm in diameter.

Trial design

Treatments tested in this trial

  • FODMAP diet

Treatment groups

150 Participants
are divided into 2 treatment groups