Effect of HIgh-flow Therapy in Long-term Oxygen Therapy

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSkane University Hospital

About this trial

This is a registry-based, randomized, controlled clinical trial of the effect of added high-flow oxygen therapy (using the device Lumis HFT) during one year in people with long-term oxygen therapy (LTOT) for chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD).

Eligibility criteria

Qualifiers

Age 40 years or older

Ongoing LTOT: prescribed for at least 15 hours per day; and since at least 28 days as registered in Swedevox

COPD or ILD as main underlying reason for LTOT

Oxygen concentrator as stationary oxygen source in the home including night-time

Disqualifiers

Current or previous treatment with home HFOT

Current treatment with home mechanical ventilation

Current treatment with home CPAP

Hospitalized during the last 2 weeks

Trial design

Treatments tested in this trial

  • Added high-flow oxygen therapy
  • Standard care

Treatment groups

310 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Skane University Hospital

Lead sponsor

Uppsala University Hospital

Collaborator

Region Stockholm

Collaborator

Region Örebro County

Collaborator

Blekinge County Council Hospital

Collaborator

Blekinge Institute of Technology

Collaborator

Lund University

Collaborator

Region Östergötland

Collaborator

Vastra Gotaland Region

Collaborator

Region Västerbotten

Collaborator

Landstinget i Värmland

Collaborator

ResMed

Collaborator

Swedish Heart Lung Foundation

Collaborator

The Swedish Research Council

Collaborator