About this trial
The goal of this observational study is to evaluate whether hypothermia affects the relationship between electroencephalography-derived indices during cardiac surgery in adult patients undergoing cardiopulmonary bypass.
The main questions it aims to answer are:
Does the correlation between Bispectral Index (BIS) and Patient State Index (PSI) change between normothermic and hypothermic phases during cardiopulmonary bypass? How do BIS and PSI values change in response to decreasing body temperature?
Participants will:
Undergo standard general anesthesia for elective on-pump coronary artery bypass surgery Be monitored simultaneously with BIS and PSI devices during surgery Have data recorded at predefined temperature-based time points during cardiopulmonary bypass
Eligibility criteria
Qualifiers
Age ≥18 years
Elective on-pump Coronary Artery Bypass Grafting (CABG) surgery
Planned use of general anesthesia
Written informed consent
Disqualifiers
Preexisting neurological disease
Use of medications affecting Electroencephalography (e.g., antiepileptics)
Severe hepatic dysfunction
Emergency surgery
Trial design
Treatments tested in this trial
- Simultaneous BIS and PSI Monitoring