Effect of Hypothermia on BIS and PSI Correlation During Cardiopulmonary Bypass

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorSakarya University

About this trial

The goal of this observational study is to evaluate whether hypothermia affects the relationship between electroencephalography-derived indices during cardiac surgery in adult patients undergoing cardiopulmonary bypass.

The main questions it aims to answer are:

Does the correlation between Bispectral Index (BIS) and Patient State Index (PSI) change between normothermic and hypothermic phases during cardiopulmonary bypass? How do BIS and PSI values change in response to decreasing body temperature?

Participants will:

Undergo standard general anesthesia for elective on-pump coronary artery bypass surgery Be monitored simultaneously with BIS and PSI devices during surgery Have data recorded at predefined temperature-based time points during cardiopulmonary bypass

Eligibility criteria

Qualifiers

Age ≥18 years

Elective on-pump Coronary Artery Bypass Grafting (CABG) surgery

Planned use of general anesthesia

Written informed consent

Disqualifiers

Preexisting neurological disease

Use of medications affecting Electroencephalography (e.g., antiepileptics)

Severe hepatic dysfunction

Emergency surgery

Trial design

Treatments tested in this trial

  • Simultaneous BIS and PSI Monitoring

Treatment groups

60 Participants
are divided into 1 treatment group

Sponsors and collaborators