This study investigates the effects of three extrinsic PEEP settings-5 cmH2O, 0 cmH2O, and an individualized PEEP (70% of the measured intrinsic PEEP)-on intrinsic PEEP and hemodynamic stability in patients with intrinsic PEEP undergoing lung resection surgery, using a randomized, crossover design.
American Society of Anesthesiologists Physical Status I - III
The Eastern Cooperative Oncology Group Performance Status Grade 0 - 2
Lung resection surgery requiring one-lung ventilation for over 60 minutes
Indication of double-lumen endobronchial tube (female 35 Fr, male 37 Fr)
Large bullae
Emergency surgery
Mechanical ventilation before surgery
Hemodynamic instability before surgery