Effect of Instrumentation Systems and Sealers on Postoperative Pain
ConditionIrriversible Pulpitis
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorEuropean University of Lefke
About this trial
The goal of this randomized clinical trial is to evaluate whether different root canal preparation systems and sealer types affect postoperative pain after root canal treatment in adult patients (18-60 years) with asymptomatic irreversible pulpitis in mandibular premolars.
The main questions it aims to answer are:
Do different instrumentation systems (TruNatomy vs ProTaper Gold) influence postoperative pain levels? Do different sealer types (AH Plus vs TotalFill BC) affect postoperative pain and analgesic consumption? Researchers will compare TruNatomy and ProTaper Gold systems combined with AH Plus or TotalFill BC sealers to determine their effect on postoperative pain.
Participants will:
Undergo single-visit root canal treatment using one of the assigned file system and sealer combinations Record their pain levels using a Numerical Rating Scale (NRS) at specific time intervals (6, 12, 24, 48, 72 hours, and 7 days) Take ibuprofen only if needed and record analgesic intake Attend a follow-up visit on the 7th day
Eligibility criteria
Qualifiers
Asymptomatic teeth with delayed positive response to thermal and electric pulp testing
Vital teeth with signs of irreversible pulpitis
Mature mandibular first or second premolars
Periodontally healthy teeth
Disqualifiers
Patients with systemic conditions (e.g., diabetes, immunocompromised status, pregnancy)
Antibiotic use within the past month
Use of analgesics within 7 days prior to treatment
Known allergy to materials used
Trial design
Treatments tested in this trial
- TruNatomy
- ProTaper Gold
- AH Plus
- TotalFill BC
Treatment groups
144 Participants
are divided into 4 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov