Effect of Intermittent Enteral Feeding in Severe Stroke
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorXijing Hospital
About this trial
This is a single-center, randomized, exploratory clinical trial investigating whether intermittent enteral feeding improves outcomes compared to continuous feeding in patients with severe stroke. The study will enroll 60 patients to evaluate the impact on 90-day all-cause mortality, neurological function, nutritional status, and safety. It will also explore underlying mechanisms through analysis of metabolic profiles, circadian gene expression, and gut microbiota.
Eligibility criteria
Qualifiers
Age ≥18 years old
It was definitely diagnosed as acute stroke by clinical imaging.
Enteral nutrition program can be started within 72 hours of onset.
Baseline GCS≤12 or NIHSS≥11
Disqualifiers
Before joining the group, he had received total parenteral nutrition treatment.
There are contraindications to enteral nutrition.
Unstable vital signs
Dementia or severe disability before onset (mRS≥3)
Trial design
Treatments tested in this trial
- Intermittent Enteral Feeding
- Continuous Enteral Feeding
Treatment groups
60 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov