Effect of Lactobacillus Johnsonii or White Pomegranate Extract on the Vaginal Health
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age20-45
SponsorChung Shan Medical University
About this trial
The goal of this clinical trial is to explore the effect of Lactobacillus johnsonii and white pomegranate extract on female bacterial status, it aims to answer are:
* Evaluate Lactobacillus johnsonii TCI250 probiotics or white pomegranate extract in regulating female vaginal bacteria and improving vaginal health. * Evaluate Lactobacillus johnsonii TCI250 probiotics or white pomegranate extract in regulating inflammation.
Participants will be randomly assigned to placebo (n = 50), probiotic heat-killed Lactobacillus johnsonii TCI250 group (n = 50) and white pomegranate extract group (n = 50) for 8 weeks. Researchers will compare the vaginal flora and inflammation.
Eligibility criteria
Qualifiers
Females aged 20-45
Nugent score ≥ 4
Menstrual cycle of 28-60 days
Disqualifiers
Pregnant or lactating women
Antibiotic usage
Other reproductive-related inflammatory diseases (e.g., candidiasis, gonorrhea, chlamydia infection)
Allergy to probiotics or White Pomegranate-related components
Trial design
Treatments tested in this trial
- Lactobacillus johnsonii, Placebo Comparator: White pomegranate extract
Treatment groups
150 Participants
are divided into 2 treatment groupsSponsors and collaborators
Chung Shan Medical University
Lead sponsor
TCI Co., Ltd.
Collaborator
Source ClinicalTrials.gov