About this trial
The goal of this clinical trial is to know the effect of multicomponent exercise in frail elderly in community to aging hallmarks. The main question\[s\] it aims to answer are:
1. Do global DNA methylation levels change in elderly people in Bandung after receiving modified poco-poco exercise? 2. Do GDF15 levels change in elderly people in Bandung after they are given modified poco-poco exercise? 3. Do lamin A COP levels change in elderly people in Bandung after they are given modified poco-poco exercise? 4. Does the level of frailty in elderly people in Bandung change after they are given modified poco-poco exercise?
Participants will be asked to do flexibility, balance, aerobic and strengthening exercise included in poco-poco modified exercise three times a week for 12 weeks
Eligibility criteria
Qualifiers
Frailty level is in pre-frailty
MoCA INA score above 18
Domicile in Bandung City
Willing to participate in the study after informed consent
Disqualifiers
There is a hearing impairment that may prevent the subject from receiving verbal instructions
There is uncorrected visual impairment
There are musculoskeletal disorders so that they cannot perform exercise procedures or procedures for measuring research variables
Subjects received other rehabilitation programs
Trial design
Treatments tested in this trial
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION