Effect of Morus Nigra Mouthwash on Gingivitis Treatment
ConditionGingivitis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorInonu University
About this trial
The aim of this study is to evaluate the clinical, microbiological, and biochemical effects of Morus nigra (black mulberry) mouthwash when used as an adjunct to non-surgical periodontal treatment (scaling and root planing - SRP) in patients with generalized gingivitis. Participants will be randomly assigned to two groups: one receiving SRP only, and the other receiving SRP plus Morus nigra mouthwash twice daily for 14 days. Clinical parameters, cytokine levels in gingival crevicular fluid (TNF-alpha, IL-1beta, IL-10), and subgingival bacterial load will be assessed at baseline, 1 month, and 3 months.
Eligibility criteria
Qualifiers
Diagnosis of generalized gingivitis (Gingival Index > 1).
Presence of at least 20 natural teeth.
Systemically healthy individuals.
Ability to provide informed consent.
Disqualifiers
Smoking or use of tobacco products.
Presence of periodontitis (no clinical attachment loss).
Use of antibiotics or anti-inflammatory drugs in the last 6 months.
Pregnancy or lactation.
Trial design
Treatments tested in this trial
- Scaling and Root Planing
- Morus Nigra Mouthwash
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov