Effect of Periodontal Therapy on Asprosin in Stable Angina

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorOndokuz Mayıs University

About this trial

This study aims to evaluate the effect of non-surgical periodontal therapy on serum asprosin levels in patients with stable angina and periodontitis. Asprosin is a novel metabolic biomarker reported to have potential protective roles in cardiovascular diseases and inflammatory processes. The study also investigates the relationship between periodontal parameters and serum asprosin levels before and after periodontal therapy.

Eligibility criteria

Qualifiers

Willingness to participate in the study and provide written informed consent

Age 18 years or older

No periodontal treatment within the past 6 months

No use of local or systemic antibiotics within the past 3 months

Disqualifiers

Unwillingness to participate in the study or to provide informed consent

Age under 18 years

Use of local or systemic antibiotics for the treatment of widespread infection within the past 3 months

Receipt of periodontal treatment within the past 6 months

Trial design

Treatments tested in this trial

  • Non-surgical periodontal therapy (scaling and root planing)
  • Non-surgical periodontal therapy (Professional dental cleaning)

Treatment groups

60 Participants
are divided into 3 treatment groups

Sponsors and collaborators