About this trial
The goal of this prospective observational cohort study is to assess the impact of perioperative sleep quality on the development of chronic post-surgical pain (CPSP) in adult patients (aged 18-80 years, ASA I-III) undergoing elective video-assisted thoracic surgery (VATS), modified radical mastectomy (MRM), or coronary artery bypass grafting (CABG). The main questions it aims to answer are:
Does poor perioperative sleep quality increase the risk of CPSP at 3 months post-surgery? How do subjective and objective sleep parameters (e.g., total sleep duration, deep sleep time) correlate with CPSP and recovery outcomes? Researchers will compare patients with varying perioperative sleep quality levels (assessed via the Richards-Campbell Sleep Questionnaire \[RCSQ\] and wearable device data) to evaluate differences in CPSP incidence, pain and quality of life.
Participants will:
Wear a Huawei wearable device to collect objective sleep data (e.g., sleep duration, deep sleep time) during hospitalization.
Complete questionnaires preoperatively and postoperatively, including RCSQ, Pittsburgh Sleep Quality Index (PSQI), Hospital Anxiety and Depression Scale (HADS), and Brief Pain Inventory (BPI).
Undergo follow-up assessments at 1, 3, and 6 months post-surgery to evaluate pain scores , CPSP status, and quality of life (SF-36).
Eligibility criteria
Qualifiers
Aged 18-80 years.
Scheduled for elective video-assisted thoracic surgery (VATS).
Scheduled for elective modified radical mastectomy (MRM).
Scheduled for elective coronary artery bypass grafting (CABG).
Disqualifiers
History of surgery within the past 3 months.
Chronic use of opioids or sedatives (defined as use for 3 months or longer).
Expected completion time of surgery after 16:00 on the day of operation.
Planned transfer to the intensive care unit (ICU) postoperatively.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
Peking Union Medical College Hospital
Lead sponsor
Chinese Academy of Medical Sciences, Fuwai Hospital
Collaborator
National Cancer Center, China
Collaborator