Effect of Perioperative Sleep Quality on Chronic Post-Surgical Pain

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorPeking Union Medical College Hospital

About this trial

The goal of this prospective observational cohort study is to assess the impact of perioperative sleep quality on the development of chronic post-surgical pain (CPSP) in adult patients (aged 18-80 years, ASA I-III) undergoing elective video-assisted thoracic surgery (VATS), modified radical mastectomy (MRM), or coronary artery bypass grafting (CABG). The main questions it aims to answer are:

Does poor perioperative sleep quality increase the risk of CPSP at 3 months post-surgery? How do subjective and objective sleep parameters (e.g., total sleep duration, deep sleep time) correlate with CPSP and recovery outcomes? Researchers will compare patients with varying perioperative sleep quality levels (assessed via the Richards-Campbell Sleep Questionnaire \[RCSQ\] and wearable device data) to evaluate differences in CPSP incidence, pain and quality of life.

Participants will:

Wear a Huawei wearable device to collect objective sleep data (e.g., sleep duration, deep sleep time) during hospitalization.

Complete questionnaires preoperatively and postoperatively, including RCSQ, Pittsburgh Sleep Quality Index (PSQI), Hospital Anxiety and Depression Scale (HADS), and Brief Pain Inventory (BPI).

Undergo follow-up assessments at 1, 3, and 6 months post-surgery to evaluate pain scores , CPSP status, and quality of life (SF-36).

Eligibility criteria

Qualifiers

Aged 18-80 years.

Scheduled for elective video-assisted thoracic surgery (VATS).

Scheduled for elective modified radical mastectomy (MRM).

Scheduled for elective coronary artery bypass grafting (CABG).

Disqualifiers

History of surgery within the past 3 months.

Chronic use of opioids or sedatives (defined as use for 3 months or longer).

Expected completion time of surgery after 16:00 on the day of operation.

Planned transfer to the intensive care unit (ICU) postoperatively.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

1,138 Participants
are grouped into 1 trial group

Sponsors and collaborators

Peking Union Medical College Hospital

Lead sponsor

Chinese Academy of Medical Sciences, Fuwai Hospital

Collaborator

National Cancer Center, China

Collaborator