Effect of Post-suction Recruitment on Lung Volume in Mechanically Ventilated ICU Patients

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Hospitalier Intercommunal de Toulon La Seyne sur Mer

About this trial

Patients who are intubated and mechanically ventilated in the intensive care unit (ICU) require repeated endotracheal suctioning to remove airway secretions. Although this procedure is necessary, it can cause a temporary collapse of lung units (alveolar derecruitment), leading to a decrease in lung volume and impaired oxygenation.

A recruitment maneuver consists of briefly applying a higher airway pressure after suctioning in order to reopen collapsed lung areas and restore lung volume. However, the clinical benefit of performing a recruitment maneuver systematically after suctioning remains uncertain.

This study aims to evaluate whether performing a recruitment maneuver immediately after closed-circuit endotracheal suctioning improves lung volume compared with suctioning alone. Lung volume will be assessed using electrical impedance tomography (EIT), a non-invasive bedside imaging technique that allows real-time monitoring of lung aeration.

In a randomized crossover design, each patient will undergo two suctioning procedures: one followed by a recruitment maneuver and one without, in a random order. The main outcome will be the change in end-expiratory lung volume 15 minutes after suctioning. The results may help optimize ventilatory care in mechanically ventilated ICU patients.

Eligibility criteria

Qualifiers

Adults aged ≥18 years

Covered by national health insurance

Admitted to the intensive care unit

Intubated and mechanically ventilated

Disqualifiers

Contraindication to electrical impedance tomography (e.g. pacemaker, implantable cardioverter-defibrillator, or implanted electrical stimulation device)

Contraindication to recruitment maneuvers (e.g. emphysema, undrained pneumothorax, hemodynamic instability)

Refractory intracranial hypertension

Acute respiratory distress syndrome requiring prone positioning

Trial design

Treatments tested in this trial

  • Suction + Recruitment maneuver
  • Closed-circuit endotracheal suctioning

Treatment groups

32 Participants
are divided into 2 treatment groups