About this trial
The main objective of this study is to evaluate the acute effects of prebiotic sodas on postprandial levels of glucagon-like peptide-1 (GLP-1), peptide YY (PYY), gastric emptying, and satiety levels in healthy adults.
Eligibility criteria
Qualifiers
Adults aged 18-60 years, inclusive.
BMI between 18.0 and 30.0 kg/m2.
Stable weight in the last 3 months (+/-5kg).
Willing to abstain from unusual strenuous exercise, consuming alcoholic drinks and from taking fiber supplements for 24 hours before study days.
Disqualifiers
Self-reported pregnant or breastfeeding women.
Subjects with a history of severe food allergies or an allergy to acetaminophen.
Known history of diabetes, any gastrointestinal disorder that alters the absorption of nutrients, liver disease, or the presence of any health condition, illness or drug use that increases risk to the subject or to others or may affect the results, as judged by the Qualified Investigator (QI).
Subjects who are currently or in the last 2 months have been on oral or injectable GLP-1 receptor agonist (RA) medications.
Trial design
Treatments tested in this trial
- Control Soda
- Prebiotic Soda - Shelf Stable
- Prebiotic Soda - Refrigerated
- Prebiotic Soda - Shelf Stable + Functional Ingredient
Treatment groups
Sponsors and collaborators
Olipop, PBC
Lead sponsor
INQUIS Clinical Research
Collaborator