Effect of Prebiotic Sodas on Postprandial Levels of GLP-1, PYY, Transit Time and Satiety Levels: A Pilot Study

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorOlipop, PBC

About this trial

The main objective of this study is to evaluate the acute effects of prebiotic sodas on postprandial levels of glucagon-like peptide-1 (GLP-1), peptide YY (PYY), gastric emptying, and satiety levels in healthy adults.

Eligibility criteria

Qualifiers

Adults aged 18-60 years, inclusive.

BMI between 18.0 and 30.0 kg/m2.

Stable weight in the last 3 months (+/-5kg).

Willing to abstain from unusual strenuous exercise, consuming alcoholic drinks and from taking fiber supplements for 24 hours before study days.

Disqualifiers

Self-reported pregnant or breastfeeding women.

Subjects with a history of severe food allergies or an allergy to acetaminophen.

Known history of diabetes, any gastrointestinal disorder that alters the absorption of nutrients, liver disease, or the presence of any health condition, illness or drug use that increases risk to the subject or to others or may affect the results, as judged by the Qualified Investigator (QI).

Subjects who are currently or in the last 2 months have been on oral or injectable GLP-1 receptor agonist (RA) medications.

Trial design

Treatments tested in this trial

  • Control Soda
  • Prebiotic Soda - Shelf Stable
  • Prebiotic Soda - Refrigerated
  • Prebiotic Soda - Shelf Stable + Functional Ingredient

Treatment groups

15 Participants
are divided into 4 treatment groups

Sponsors and collaborators

Olipop, PBC

Lead sponsor

INQUIS Clinical Research

Collaborator