Effect of Preoperative Oral Carbohydrate Loading on Postoperative Outcomes in Liver Transplant Patients

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMedical University of Warsaw

About this trial

The aim of the study is to evaluate the effect of preoperative oral carbohydrate loading on postoperative outcomes in liver transplant recipients. The results of this study may contribute to improving recovery after liver transplantation and shortening postoperative hospital stay in these patients.

Participants will be randomly assigned to either the study group or the control group. Patients assigned to the study group will receive 400 mL of a carbohydrate beverage (Nutricia preOp®), to be consumed up to 2 hours before the anesthesia induction. Patients assigned to the control group will receive 400 mL of a placebo administered in an identical manner as in the study group. Participants will not be informed which group they have been assigned to.

In the postoperative period, routine laboratory and imaging tests will be performed, and their results will be used to assess the effects of the intervention. Follow-up of the patient's clinical course is planned for up to 30 days after surgery. The schedule of follow-up visits will not differ from standard clinical practice.

Eligibility criteria

Qualifiers

age ≥ 18 years

elective liver transplantation at the Department of General, Transplant, and Liver Surgery, Medical University of Warsaw

grafts from brain-dead donors

MELD score <35

Disqualifiers

acute liver failure

insulin-dependent diabetes mellitus

gastroparesis

mechanical bowel obstruction

Trial design

Treatments tested in this trial

  • Preoperative Oral Carbohydrate Loading
  • Placebo

Treatment groups

434 Participants
are divided into 2 treatment groups

Sponsors and collaborators