Effect of Resistance Training in Patients on the Waiting List for Heart Transplant
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorUniversity of Sao Paulo General Hospital
About this trial
The present longitudinal, randomized, and blinded clinical trial aims to:
* Evaluate the effects of resistance training on the functional capacity, quality of life, and cardiac biomarkers of hospitalized patients with heart failure (HF) on the waiting list for heart transplantation (HTx). * Evaluate the associations between Fried's frailty classification and functional capacity responses to resistance training.
The protocol will have a total duration of 12 weeks.
Eligibility criteria
Qualifiers
patients included in heart transplant list ≤1 month
hemodynamically stable in the last 48 hours defined as mean arterial pressure (MAP) ≥ 60 mmHg and ≤ 120 mmHg and - Heart rate (HR) ≥ 60 bpm and ≤ 120 mmHg.
dobutamine dose ≤ 10 mcg/kg/min
Disqualifiers
heart failure of arrhythmogenic and/or restrictive etiology
presence of uncontrolled acute arrhythmias
cognitive, orthopedic, or neuromotor changes that prevent functional tests from being carried out
Trial design
Treatments tested in this trial
- Resistance Training Program
- Standard Treatment Group
Treatment groups
50 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Sao Paulo General Hospital
Lead sponsor
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Collaborator
Source ClinicalTrials.gov