Effect of Sodium Chloride 5% Solution as an Adjuvant Treatment With Antimicrobial Therapy in the Treatment of Bacterial Infectious Keratitis

ConditionsInfectious Keratitis Adjuvant Treatment Bacterial Infectious Keratitis Sodium Chloride 5% Solution

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-60

SponsorSohag University

About this trial

This study aims to detect the effect of sodium chloride 5% solution as an adjuvant treatment with antimicrobial therapy in treatment of bacterial infectious keratits and to assess whether NaCl 5% accelerates epithelial healing, improves microbial eradication, and enhances visual outcomes in bacterial infectious keratitis.

Eligibility criteria

Qualifiers

Clinically diagnosed bacterial infectious keratitis

Positive corneal scraping or strong clinical suspicion of bacterial cause.

Ability to provide informed consent and attend follow-up visits

Disqualifiers

• Fungal, viral, or acanthamoeba keratitis.

Recent (<7 days) topical corticosteroid use.

Corneal perforation or impending perforation.

History of hypersensitivity to study agents.

Trial design

Treatments tested in this trial

Sodium chloride 5% solution
quinolones

Treatment groups

40 Participants

are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Sohag University

Lead sponsor

Source ClinicalTrials.gov