Effect of St. John's Wort in the Treatment of Recurrent Aphthous Stomatitis
ConditionStomatitis, Aphthous
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorBatman University
About this trial
The aim of the treatment of Recurrent Aphthous Stomatitis (RAS) is to accelerate the healing of ulcers by reducing pain and inflammation, thus enabling patients to perform their oral functions comfortably. It has been said many times in the literature that St. John's wort is very effective in wound healing.In this study, the evaluation of the therapeutic effects of St. John's wort extract on the clinical symptoms and ulcer healing rate in patients with Recurrent Aphthous Stomatitis (RAS), a condition with no definitive treatment, was aimed.
Eligibility criteria
Qualifiers
18 years and over
Having a history of RAS for at least 2 years
Having one in an easily accessible area in the mouth
RAS has not exceeded a period of 48 hours
Disqualifiers
Having any allergic history to these substances to be applied
During pregnancy and lactation
Use of steroids, vitamins, antibiotics, antihistamines, oral retinoids or immune system regulating agents for ulcer treatment within 3 months
The patient has a history of systemic disease
Trial design
Treatments tested in this trial
- Kenacort A Orabase® pomad , Bristol-Myers Squibb İlaçları Inc. İstanbul , Türkiye
- Hyaluronic acid, Aftamed ® Oral jel , AktiFarma . İstanbul, Türkiye
- St. John's wort oil, Zade Vital; Health&Fitness, Developed With Ege Üniversiesi Argefar
Treatment groups
75 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov