Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases

ConditionsMild Cognitive Impairment (MCI) Amnestic Lewy Body Disease With Mild Cognitive Impairment Parkinson's Disease With Mild Cognitive Impairment

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age60-80

SponsorMasaryk University

About this trial

The purpose of this study is to investigate the immediate effects of non-invasive temporal interference stimulation (TIS) targeting the striatum on sentence processing and brain connectivity in patients with neurodegenerative diseases.

Eligibility criteria

Qualifiers

Possible or probable Mild Cognitive Impairment with Lewy Bodies (MCI-LB), in Parkinson's Disease (MCI-PD) or Amnestic Mild Cognitive Impairment (aMCI).

Disqualifiers

Any severe psychiatric disorder.

History of other neurological diseases affecting the central nervous system.

Severe head trauma.

Uncompensated internal or oncological disease.

Trial design

Treatments tested in this trial

Active Temporal Interference Stimulation (TIS)
Placebo / Sham TIS

Treatment groups

70 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Masaryk University

Lead sponsor

Source ClinicalTrials.gov