The randomized controlled study which compare the efficacy outcomes (reducing blood loss and drainage output in patients) in patients undergoing single-level minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) and received topical tranexamic acid injection in the surgical site to those who received placebo injection.
Age 30-80 years old
Degenerative spine problems including spinal stenosis, disc degeneration, spondylolithesis that indicated for single level MI-TLIF
Revision surgery
Patients who had high risk of complication from TXA
History of seizure, PE, DVT, thromboembolic episode
History of TXA allergy
Thanawan Longsuwan
Lead sponsor
Ramathibodi Hospital
Sponsor institution