Effect of Transcranial Alternating Current Stimulation(tACS) for Early Alzheimer's Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-85
SponsorAnhui Medical University

About this trial

To investigate the clinical effect neural mechanism of transcranial alternating current stimulation in early Alzheimer's disease

Eligibility criteria

Qualifiers

Subject diagnosed with early Alzheimer's disease or related diseases according to NIA-AA criteria.

Subjects must have a MMSE score between 10 and 27,indicating mild cognitive impairment or dementia.

CDR score ≤ 2.

Subject under treatment by IAChE for at least 3 months.

Disqualifiers

CDR > 2

Any history or clinical signs of other severe psychiatric illnesses (like major depression,psychosis or obsessive compulsive disorder).

History of head injury,stroke,or other neurologic disease.

Organic brain defects on T1 or T2 images.

Trial design

Treatments tested in this trial

  • Transcranial alternating current stimulation
  • Sham transcranial alternating current stimulation

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators