Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Opioid Consumption in Patients Undergoing Major Abdominal Surgery

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorAffiliated Hospital of Jiaxing University

About this trial

This study aims to design a prospective, double-blind, randomized controlled trial to compare the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on postoperative visceral pain in patients undergoing major abdominal surgery. Participants will be randomly assigned to receive either taVNS or sham stimulation. The total consumption of opioids and other analgesics within 24 hours post-surgery in the AICU will be recorded, along with follow-up assessments of pain scores and quality of recovery scores (Qor-15) at 24 hours postoperatively.

Eligibility criteria

Qualifiers

Age between 18 and 85 years, regardless of gender

ASA physical status classification I-III

Scheduled for elective major abdominal surgery under general anesthesia, with postoperative admission to the AICU for monitoring

Anticipated duration of stay in the AICU is approximately 24 hours

Disqualifiers

History of vagus nerve-related diseases (such as vasovagal syncope);

Severe arrhythmias or implanted electronic devices such as pacemakers;

Skin lesions, infections, or deformities at the site of external ear stimulation;

Long-term preoperative use of opioid medications or sedatives;

Trial design

Treatments tested in this trial

  • Transcutaneous auricular vagus nerve stimulation
  • Sham Transcutaneous auricular vagus nerve stimulation

Treatment groups

108 Participants
are divided into 2 treatment groups

Locations

This trial has no locations