The goal of this randomized controlled clinical trial is to investigate the effects of vitamin D3 supplementation on cardiometabolic risk in Chinese adolescents with overweight/obesity and vitamin D deficiency. The main question it aims to answer whether vitamin D3 supplementation can improve cardiovascular metabolic health.
Participants in the intervention group will receive vitamin D3. The control group will receive vitamin D placebo.
Researchers will compare the change in cardiometabolic risk from baseline to post-intervention at 12 weeks between the intervention and control groups.
Students whose caregivers signed informed consents;
Students with serum 25(OH)D concentration of 12-20 ng/mL;
Students with overweight or obesity.
Students with any disease that affects vitamin D metabolism (e.g., functional/organic brain disease, severe infectious disease, chronic gastrointestinal disease, hepatic or renal insufficiency, etc.);
Students with known chronic disease (e.g., cardiovascular disease); use of vitamin D supplements in the past 3 months;
Students with allergies to vitamin D or soybean oil ingredients.