Effect of Vitamin D on Crestal Bone Loss Around Immediate Implant After Mandibular Premolars and Molars Extraction

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-60
SponsorSuez Canal University

About this trial

What is the difference between grafting the jumping gap upon using xenograft mixed with topical vitamin D clinically regarding crestal bone level and implant stability, radiographically regarding crestal bone level after implant insertion in the posterior region of mandible?

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

The American Society of Anesthesiologist (ASA) I , II

Both Genders. 3- Patients having unrestorable tooth on the posterior mandibular region

Age>20

The patient who have complete their facial growth and teeth eruption

Disqualifiers

Poor oral hygiene patients and/or patients

Patients with active acute infection.

Patients with bad oral habits.

Pregnant or lactating women.

Trial design

Design model

Parallel

Treatments tested in this trial

  • vit D mixed with xenograft

    Drug

    Topical application of vitamin D solution mixed with xenograft in the jumping gap around immediate implant

  • only xenograft without vit D

    Drug

    grafting the jumping gap with xenograft only around immediate implant

Treatment groups

20 Participants
are divided into 2 treatment groups
Group A: vit D mixed with xenograftActive comparator 1 intervention
Group B: only xenograft without vit DPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

clinically: A)Loss of crestal bone. B)Stability of implant. Radiographically: crestal bone loss by periapical radiograph in millimeters.

the loss of crestal bone after implant insertion using periodontal probe in millimeters. implant stability using OSTELL device. Postoperative follow up using periapical radiographs to evaluate crestal bone loss in millimeters will be after, one ,three months and six months by standardized parallel periapical digital technique radiograph .The radiographs will be done by using: The Kavo Scan eXamTM One and the Rinn extension cone paralleling (XCP)periapical film holder will be used to achieve standardization of digital radiographs.

Time frame
clinically: Loss of crestal bone by periodontal prop assessed in millimeters in six months Stability of implant by OSTTEL assessed as ISQ values in six months crestal bone loss in millimeters will be one ,three months and six months.

Secondary outcomes

Other outcomes

Sponsors and contacts

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